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| Player | Team | IP | ER | BB | H | IR/Scored | Strikeouts | ERA |
|---|---|---|---|---|---|---|---|---|
| Chris Sale | Atlanta | 13.00 | 3 | 10 | 0 | 0 / 0 | 21 | 2.08 |
| Gage Jump | Athletics | 12.67 | 0 | 6 | 2 | 0 / 0 | 14 | 0.00 |
| Garrett Schoenle | Chicago (CWS) | 7.00 | 1 | 2 | 1 | 5 / 0 | 10 | 1.29 |
| Drew Rasmussen | Tampa Bay | 11.67 | 2 | 9 | 3 | 0 / 0 | 15 | 1.54 |
| Tyler Samaniego | Boston | 10.33 | 1 | 6 | 2 | 3 / 1 | 12 | 0.87 |
| Reid Detmers | Anaheim | 6.67 | 0 | 4 | 3 | 0 / 0 | 13 | 0.00 |
| Ryan Weathers | New York (NYY) | 12.67 | 3 | 7 | 5 | 0 / 0 | 15 | 2.13 |
| Dylan Dodd | Atlanta | 6.67 | 0 | 4 | 2 | 7 / 1 | 9 | 0.00 |
| Cristopher Sánchez | Philadelphia | 13.67 | 6 | 10 | 3 | 0 / 0 | 18 | 3.95 |
| Connor Prielipp | Minnesota | 11.33 | 5 | 14 | 1 | 0 / 0 | 19 | 3.97 |
| Sonny Gray | Baltimore | 12.67 | 3 | 10 | 1 | 0 / 0 | 14 | 2.13 |
| Hunter Brown | Houston | 11.33 | 3 | 7 | 7 | 0 / 0 | 16 | 2.38 |
| Jesús Luzardo | Philadelphia | 7.67 | 0 | 1 | 1 | 0 / 0 | 9 | 0.00 |
| Cam Schlittler | New York (NYY) | 12.33 | 1 | 9 | 4 | 0 / 0 | 13 | 0.73 |
| Brandon Woodruff | Milwaukee | 11.33 | 3 | 5 | 5 | 0 / 0 | 13 | 2.38 |