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| Player | Team | IP | ER | BB | H | IR/Scored | Strikeouts | ERA |
|---|---|---|---|---|---|---|---|---|
| Freddy Peralta | Milwaukee | 14.00 | 2 | 8 | 1 | 0 / 0 | 19 | 1.29 |
| Joe Ryan | Philadelphia | 12.67 | 0 | 9 | 3 | 0 / 0 | 17 | 0.00 |
| Jacob deGrom | Texas | 12.00 | 2 | 8 | 4 | 0 / 0 | 19 | 1.50 |
| Bryan Woo | Seattle | 14.00 | 2 | 12 | 1 | 0 / 0 | 18 | 1.29 |
| Cristopher Sánchez | Minnesota | 13.33 | 3 | 12 | 1 | 0 / 0 | 18 | 2.03 |
| Hunter Brown | San Diego | 14.67 | 2 | 11 | 2 | 0 / 0 | 16 | 1.23 |
| Blake Snell | Los Angeles | 11.33 | 1 | 7 | 3 | 0 / 0 | 15 | 0.79 |
| Jesús Luzardo | Philadelphia | 12.33 | 5 | 9 | 2 | 0 / 0 | 19 | 3.65 |
| Luis Castillo | Seattle | 13.33 | 4 | 8 | 2 | 0 / 0 | 16 | 2.70 |
| Kody Funderburk | Miami | 9.00 | 0 | 2 | 5 | 2 / 0 | 12 | 0.00 |
| Shohei Ohtani | Los Angeles | 5.00 | 0 | 1 | 0 | 0 / 0 | 11 | 0.00 |
| Tyler Glasnow | Los Angeles | 11.00 | 2 | 6 | 4 | 0 / 0 | 14 | 1.64 |
| Tarik Skubal | Athletics | 7.33 | 0 | 3 | 0 | 0 / 0 | 10 | 0.00 |
| Merrill Kelly | Arizona | 14.33 | 3 | 11 | 0 | 0 / 0 | 13 | 1.88 |
| Hunter Greene | Cincinnati | 12.33 | 6 | 10 | 4 | 0 / 0 | 19 | 4.38 |
| Logan Gilbert | Seattle | 7.00 | 0 | 4 | 1 | 0 / 0 | 10 | 0.00 |
| Michael King | San Diego | 12.33 | 3 | 10 | 4 | 0 / 0 | 15 | 2.19 |
| Tyler Wells | Baltimore | 6.33 | 0 | 1 | 0 | 0 / 0 | 8 | 0.00 |
| Connelly Early | Boston | 11.33 | 6 | 9 | 4 | 0 / 0 | 18 | 4.76 |