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| Player | Team | IP | ER | BB | H | IR/Scored | Strikeouts | ERA |
|---|---|---|---|---|---|---|---|---|
| Logan Gilbert | Seattle | 14.00 | 0 | 11 | 2 | 0 / 0 | 19 | 0.00 |
| Paul Skenes | Pittsburgh | 13.67 | 2 | 8 | 0 | 0 / 0 | 18 | 1.32 |
| MacKenzie Gore | Washington | 13.67 | 3 | 8 | 1 | 0 / 0 | 18 | 1.98 |
| Joe Ryan | Philadelphia | 13.00 | 1 | 9 | 3 | 0 / 0 | 18 | 0.69 |
| Ryan Pepiot | Tampa Bay | 12.33 | 2 | 6 | 1 | 0 / 0 | 16 | 1.46 |
| Tarik Skubal | Detroit | 8.00 | 1 | 7 | 0 | 0 / 0 | 15 | 1.13 |
| Garrett Crochet | Boston | 13.00 | 1 | 9 | 3 | 0 / 0 | 14 | 0.69 |
| Jacob deGrom | Texas | 13.67 | 3 | 6 | 4 | 0 / 0 | 14 | 1.98 |
| Reese Olson | Detroit | 10.33 | 5 | 9 | 4 | 0 / 0 | 19 | 4.35 |
| Yariel Rodríguez | Toronto | 9.33 | 4 | 3 | 3 | 5 / 0 | 12 | 3.86 |
| Bryan Woo | Seattle | 13.33 | 1 | 7 | 3 | 0 / 0 | 11 | 0.68 |
| Kevin Kelly | Tampa Bay | 8.00 | 3 | 4 | 2 | 6 / 1 | 11 | 3.38 |
| Ranger Suárez | Kansas City | 8.00 | 1 | 2 | 1 | 0 / 0 | 9 | 1.13 |
| Daniel Palencia | Arizona | 6.00 | 0 | 3 | 1 | 7 / 0 | 7 | 0.00 |
| Zack Wheeler | Philadelphia | 6.00 | 1 | 3 | 2 | 0 / 0 | 11 | 1.50 |